Medical Research Archive

Science has made astonishing progress in the past 60 years in many areas. Examples include the ability to repair certain defective genes, use stem cells to treat certain diseases, detect and fight many cancers, fight viruses with medications, make organ transplants work, and prevent disease with vaccines and lifestyle changes. Thanks to technological advances, doctors can also see clearly inside the body and use artificial intelligence to speed the development of new medications.

A new study from the National Institutes of Health has performed more diverse and extensive biological measurements of people experiencing chronic fatigue syndrome than any previous research. Here's what they found and what it means.

If you've ever tried to lose weight, you've probably heard the advice to drink water before a meal because it makes you feel fuller and you'll stop eating sooner. It seems like a reasonable idea — but does it work? And if it doesn't, why do people think it does?

Even though motorcycles are riskier than other modes of transportation, the number of motorcycles registered in the US has doubled in the past 20 years. A study examined whether large gatherings of bikers would lead to more fatal accidents and an increase in rates of organ donation.

When prostate cancer spreads beyond the gland, it has been treated with hormone therapy, but there are challenging side effects. A new study shows that a different treatment option involving radiation can allow some men to delay or avoid hormone therapy.

Harvard Medical School has created a large department dedicated to developing and teaching young scientists about the emerging field of computational medicine. This field uses new mathematical techniques to make sense of the thousands of numbers generated in experiments measuring various molecules. Analyzing such "big data" was once unimaginable. Now, scientists have the tools to do it, and to compare tissue of people with and without a disease to find out which molecules are different.

A trial from 2019 showed a medication dramatically reduced triglyceride levels in participants, but subsequent analysis found that the placebo used in the trial may have negatively affected those assigned to take it.

The vast majority of diseases do not have a single cause; rather, multiple factors combine to cause a disease. Growing evidence suggests that several viruses may be triggers of multiple sclerosis, and a long-term study found evidence that an infection with a common virus can be an important contributing factor in MS.

In science, true breakthroughs are rare. Some are the result of fortunate accidents, while others come from scientists with the will to pursue a dream despite challenges and obstacles. And when such breakthroughs do happen –– think of penicillin or COVID vaccines –– the whole world benefits from them.

News stories frequently tout "breakthrough" drugs, but how often does this turn out to be true? When you read or hear about the results of a study for a new medication, these steps can help you ask questions to get the full story and a better sense of what it might mean for your health.